The Tip Desk

Spyre Therapeutics, Inc.

Company Stats

Market Cap
$7.9B
as of Sep 30, 2026
Shares Outstanding
88.2M
Free Float
64.3%

Income Statement

Revenue
$0
Operating Income
-$209.6M
Net Income
-$155.2M
EBITDA
-$209.6M

Balance Sheet

Cash & Equivalents
$85.7M

Returns & Capital

SBC, 3Y Avg
$36.0M

Cash Flow by Year

YearRevenueFCFMargin
FY2025$0——
FY2024$0-$157.4M—
FY2023$886,000-$99.9M-11276.5%
FY2022$2.3M-$80.2M-3442.8%
FY2021$18.7M-$54.3M-289.7%

Annual filing data through FY ended December 31, 2025; shares and float as of November 1, 2026. Yields and enterprise value use the calculated market cap above, at its as-of date. Ratios are our calculations from reported figures.

Earnings

Other Coverage