The Tip Desk

IONIS PHARMACEUTICALS INC

Company Stats

Market Cap
$7.4B
as of Sep 30, 2026
Shares Outstanding
166.2M
Free Float
99.3%

Income Statement

Revenue
$943.7M
Operating Income
-$381.7M
Net Income
-$381.4M
EBITDA
-$371.7M
Non-cash Impairment
$986,000
Revenue Growth, 3Y
17.1%
FCF Margin, 3Y Avg
-51.1%
FCF Margin, Worst Year
-77.5%

Cash Flow

Free Cash Flow
-$320.0M
FCF Yield
-4.3%
Owner FCF Yield
-6.1%

Balance Sheet

Cash & Equivalents
$372.3M

Returns & Capital

SBC, 3Y Avg
$123.3M

Cash Flow by Year

YearRevenueFCFMargin
FY2025$943.7M-$320.0M-33.9%
FY2024$705.1M-$546.2M-77.5%
FY2023$787.6M-$331.3M-42.1%
FY2022$587.4M-$290.1M-49.4%
FY2021$810.5M$18.8M2.3%

Annual filing data through FY ended December 31, 2025; shares and float as of October 8, 2026. Yields and enterprise value use the calculated market cap above, at its as-of date. Ratios are our calculations from reported figures.

Earnings

Other Coverage